α-Burke 2
Analytical and Semi-Preparative Columns
The α-Burke 2 phase is derived from dimethyl N-3,5-dinitro-benzoyl--amino-2,2-dimethyl- 4-pentenyl phosphonate covalently bound to 5 µm silica. This π-acceptor chiral stationary phase is particularly valuable in the HPLC separation of β-blocker enantiomers, an important class of cardiovascular drugs whose enantiomers often exhibit differing pharmacological activities. The α-Burke 2 has been specifically designed to separate the enantiomers of β-blockers without chemical derivatization. In addition, it also resolves the enantiomers of many compounds separated on π-acceptor Pirkle type chiral stationary phases.
| Product | Particle Size | Column Dimensions | Regis
Product # | U.S. Price |
| Spherical Silica |
| (R)-a-Burke 2 | 5 µm, 100 Å | 25 cm x 10.0 mm i.d. | 735235 | $5,000.00 |  |
| (R)-a-Burke 2 | 5 µm, 100 Å | 25 cm x 21.1 mm i.d. | 735236 | $11,000.00 | call to buy |
| (R)-a-Burke 2 | 5 µm, 100 Å | 25 cm x 4.6 mm i.d. | 735035 | $1,500.00 | |
| (S)-a-Burke 2 | 5 µm, 100 Å | 25 cm x 10.0 mm i.d. | 735237 | $5,000.00 | |
| (S)-a-Burke 2 | 5 µm, 100 Å | 25 cm x 21.1 mm i.d. | 735238 | $11,000.00 | call to buy |
| (S)-a-Burke 2 | 5 µm, 100 Å | 25 cm x 4.6 mm i.d. | 735037 | $1,500.00 | |