GC Chiral Derivatization

GC analysis of enantiomeric compounds on nonracemic or achiral stationary phases requires the use of enatiopure derivatization reagents. These reagents generally target one specific functional group to produce diastereomers of each of the enantiomeric analytes. From the resulting chromatograms, calculations are conducted to determine the enantiomeric concentration of the analyte.

• GC determination of enantiomeric purity is facilitated by using enantiopure derivatization reagents
• These derivatization reagents produce covalent diastereomers of the enantioenriched analytes
• TPC (N-TFA-L-Propyl Chloride) and MCF (1R, 2S, 5R-L-7-Menthylchloroformate trifluoracetyl) are the most commonly used derivatization reagents

Product	Size	Regis Product #	U.S. Price
TPC
TPC	25 gram	440001	$100.00
MCF
MCF	25 gram	440003	$100.00
MTPA
(R)-(-)-MTPA-Cl, Mosher's acid chloride	100mg	270900	$60.00
(R)-(-)-MTPA-Cl, Mosher's acid chloride	500mg	270901	$240.00
(R)-(-)-MTPA-Cl, Mosher's acid chloride	1000mg	270902	$400.00