Fluorinated Anhydrides: HFBA

HFBA is an Acylation Reagent for GC Derivatization that is most commonly used for ECD and reacts with alcholos, amines, and phenols.  Bases such as triethylamine and trimethylamine can be added to promote reactivity to HFBA.  HFBA is frequently used for the confirmation of drugs of abuse.

HFBA derivatives are most sensitive to ECD.

Physical and Chemical Properties
    Suggested Storage Conditions:    Cool Place
    Use:    Acylation Reagent for GC
    Appearance:    Clear, colorless liquid
    BP:    109-109ºC (226-228ºF)
    MW:    C₈F₁₄O₃
    FW:    410.06 g/mol
    Specific Gravity (H₂O = 1.0):    1.653

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Fluorinated Anhydrides:    HFBA; Heptafluorobutyric Anhydride
CAS [336-59-4]

Product	Size	Regis Product #	U.S. Price
HFBA	10x1 gram	270851	$77.63
HFBA	25 gram	270853	$103.50