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Whelk-O® 1

Analytical to Preparative Columns
The Whelk-O 1 is useful for the separation of underivatized enantiomers in a number of families including amides, epoxides, esters, ureas, carbamates, ethers, aziridines, phosphonates, aldehydes, ketones, carboxylic acids, alcohols and non-steroidal anti-inflammatory drugs (NSAIDs). This π-electron acceptor/π-electron donor phase exhibits an extraordinary degree of generality. The broad versatility observed on the Whelk-O 1 column compares favorably with polysaccharidederived chiral stationary phases.

In addition, because Whelk-O 1 is covalently bonded to the support, the phase is compatible with all commonly used mobile phases, including aqueous systems — a distinct advantage over polysaccharide derived chiral stationary phases. Other advantages include column durability, excellent efficiency, ability to invert elution order and excellent preparative capacity.

ProductParticle SizeColumn DimensionsRegis
Product #
U.S. Price
Spherical Silica
(R,R)-Whelk-O 15 µm, 100Å 25 cm x 4.6 mm i.d. 786201$1,656.00
(R,R)-Whelk-O 15 µm, 100Å 25 cm x 10.0 mm i.d. 786202$5,692.50
(R,R)-Whelk-O 15 µm, 100Å 25 cm x 30.0 mm i.d. 786205$20,700.00call to buy
(S,S)-Whelk-O 15 µm, 100Å 25 cm x 4.6 mm i.d. 786101$1,656.00
(S,S)-Whelk-O 15 µm, 100Å 25 cm x 10.0 mm i.d. 786102$5,692.50
(S,S)-Whelk-O 15 µm, 100Å 25 cm x 30.0 mm i.d. 786105$20,700.00call to buy
Spherical Kromasil® Silica
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 4.6 mm i.d. 786515$1,656.00
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 10.0 mm i.d. 786525$5,692.50
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 21.1 mm i.d. 786535$12,420.00call to buy
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 30.0 mm i.d. 786708$20,700.00call to buy
(R,R)-Whelk-O 1 10 µm, 100Å 25 cm x 50.0 mm i.d. 786709$35,707.50call to buy
(R,R)-Whelk-O 1 10 µm, 100Å 50 cm x 21.1 mm i.d. 786545$20,700.00call to buy
(R,R)-Whelk-O 1 10 µm, 100Å 50 cm x 30.0 mm i.d. 786713$39,330.00call to buy
(R,R)-Whelk-O 1 10 µm, 100Å 50 cm x 50.0 mm i.d. 786710$43,987.50call to buy
(R,R)-Whelk-O 15 µm, 100Å 25 cm x 4.6 mm i.d. 780201$1,656.00
(R,R)-Whelk-O 1 5 µm, 100Å 25 cm x 10.0 mm i.d. 780202$5,692.50
(R,R)-Whelk-O 1 5 µm, 100Å 25 cm x 30.0 mm i.d. 780203$21,735.00call to buy
(R,R)-Whelk-O 1 5 µm, 100Å 25 cm x 50.0 mm i.d. 780204$51,750.00call to buy
(S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 4.6 mm i.d. 786615$1,656.00
(S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 10.0 mm i.d. 786625$5,692.50
(S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 21.1 mm i.d. 786635$12,420.00call to buy
(S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 30.0 mm i.d. 786702$20,700.00call to buy
(S,S)-Whelk-O 1 10 µm, 100Å 25 cm x 50.0 mm i.d. 786703$35,707.50call to buy
(S,S)-Whelk-O 1 10 µm, 100Å 50 cm x 21.1 mm i.d. 786645$20,700.00call to buy
(S,S)-Whelk-O 1 10 µm, 100Å 50 cm x 30.0 mm i.d. 786716$39,330.00call to buy
(S,S)-Whelk-O 1 10 µm, 100Å 50 cm x 50.0 mm i.d. 786704$43,987.50call to buy
(S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 4.6 mm i.d. 780101$1,656.00
(S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 10.0 mm i.d. 780102$5,692.50
(S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 30.0 mm i.d. 780103$21,735.00call to buy
(S,S)-Whelk-O 1 5 µm, 100Å 25 cm x 50.0 mm i.d. 780104$51,750.00call to buy