Alpha Burke 2

Category: Pirkle-type Chiral Columns
Description:

This π-acceptor chiral stationary phase is particularly valuable in the HPLC separation of β-blocker enantiomers, an important class of cardiovascular drugs whose enantiomers often exhibit differing pharmacological activities. The α-Burke 2 has been specifically designed to separate the enantiomers of β-blockers without chemical derivatization. In addition, it also resolves the enantiomers of many compounds separated on π-acceptor Pirkle type chiral stationary phases.

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Selector: dimethyl N-3,5-dinitro-benzoyl--amino-2,2-dimethyl- 4-pentenyl phosphonate
Techniques: High Performance Liquid Chromatography (HPLC) & Supercritical Fluid Chromatography (SFC)