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September 25, 2023
Method Dev Part 3_Researcher

Getting Started with Chiral Method Development Part Three: Method Development Optimization

In Part 2 of our series on Chiral Method Development, we discussed the features of several different types of chiral stationary phases (CSPs).  We also discussed a general approach to column and mobile phase screening, which can be helpful for identifying candidates to carry on for further method development and […]
April 30, 2023

Getting Started with Chiral Method Development Part Two: Finding a CSP

In a previous blog, we discussed the concept of molecular chirality and its importance.  We also noted the ability to separate enantiomers using chiral chromatography.  In this installment, we’ll talk about the first steps in developing an HPLC method that will separate chiral compounds of interest. With any approach to […]
October 14, 2022

Getting Started with Chiral Method Development

At Regis Technologies, we have a wide range of columns featuring different chiral stationary phases (CSPs), and we are often asked to recommend one that will resolve a specific set of stereoisomers.  That’s not always an easy thing to do!  But whether you’re looking to create a robust analytical method […]
April 4, 2023
Supercritical fluid chromatography (SFC) is a type of normal phase chromatography, designed much like high-performance liquid chromatography (HPLC). It uses pumps and columns to separate the different components of a complex mixture. The difference lies with the mobile phase. HPLC uses pressured liquid, whereas SFC uses a supercritical fluid.

Supercritical Fluid Chromatography: A Greener, Cheaper, and Faster Alternative in Normal Phase Chromatography

With Earth Day upon us, we are seeing a focus on how companies are trying to do their part to be environmentally friendly. Businesses worldwide are implementing green initiatives, and those initiatives may look quite different depending on the industry. In some sectors, going green means installing solar panels. In […]
December 12, 2020

6 Top Chiral Chromatography Questions

A chiral molecule is one in which the stereoisomers are mirror images of each other. These mirror images – an example of molecular symmetry – are referred to as enantiomers (see image at right – courtesy of Wikipedia). From a separation standpoint, chiral molecules pose unique challenges. Because they are […]
October 1, 2020
Welcome to the Regis Technologies Blog, where we’ll be sharing news and information about our custom pharma contract development and manufacturing services as well as our portfolio of chromatography columns and specialty reagents.

Welcome to the Regis Technologies Blog

Welcome to the Regis Technologies blog, where we’ll be sharing news and information about our custom pharma contract development and manufacturing services as well as our portfolio of chromatography columns and specialty reagents. Regis Technologies, Inc. partners with pharmaceutical and biotechnology companies to help expedite their drug candidates to market. […]