The Pirkle 1-J contains an unusual ß-lactam structure which significantly alters its molecular recognition properties. It is useful for the direct separation of underivatized ß-blocker enantiomers. It can also be used for the separation of the enantiomers of arylpropionic acid NSAIDs, as well as other drugs.
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3-(3,5-Dinitrobenzamido)-4-phenyl-β-lactam
High Performance Liquid Chromatography (HPLC) & Supercritical Fluid Chromatography (SFC)
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