Pirkle 1-J

Category: Pirkle-type Chiral Columns

The Pirkle 1-J contains an unusual β-lactam structure which significantly alters its molecular recognition properties. It is useful for the direct separation of underivatized β-blocker enantiomers. It can also be used for the separation of the enantiomers of arylpropionic acid NSAIDs, as well as other drugs.

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Selector: dimethyl N-3,5-dinitro-benzoyl--amino-2,2-dimethyl- 4-pentenyl phosphonate
Techniques: High Performance Liquid Chromatography (HPLC) & Supercritical Fluid Chromatography (SFC)