TFAA: Trifluoroacetic Anhydride

Category: Acylation Reagents
CAS # : 407-25-0
Chemical Name: Trifluoroacetic Anhydride

TFAA is most commonly used for ECD and reacts with alcohols, amines, and phenols. Bases such as triethylamine and trimethylamine can be added to promote reactivity to TFAA. TFAA is frequently used for the confirmation of drugs of abuse and is the most reactive and volatile of the anhydrides.

Regis SKU #:

Use: Acylation Reagent for GC
Appearance: Clear, colorless liquid
BP: 39.5-40ºC (103ºF)
MF: C4F6O3
FW: 210.03 g/mol
Specific Gravity (H2O = 1.0): 1.487
Suggested Storage Conditions: Cool, dry place with adequate ventilation and suitable for corrosives.