Dr. Igor Likhotvorik and a team of eight process chemists will work to develop your chemistry into robust and commercially viable procedures. This veteran team has scaled-up and optimized hundreds of challenging chemical processes. The group supports each other to overcome chemical and chemical engineering issues.

They are supported by an outstanding analytical research team with tools such as NMR and LC/MS. The Analytical Early Process Support Group takes an early look at your molecule which helps them develop robust analytical methods later.

CHEMICAL PROCESS DESIGN

PROCESS DEVELOPMENT & OPTIMIZATION

  • Optimization of yields
  • Reduction of high reaction dilutions
  • Elimination of hazardous reagents or intermediates
  • Thermochemical profiling by RC1 or DSC
  • Elimination of costly unit operations such as chromatography
  • Evaluation of safety concerns
  • Evaluation of new synthetic routes
Flow Reactor

PROCESS RESEARCH TO

PROCESS VALIDATION

Stability data for intermediates and final API
  • Identification of impurity profiles for raw materials and intermediates in the commercial process
  • Fate of impurities analyses
  • Evaluation of chemical processes for environmental health and safety issues
  • Identification of site specific needs for processing equipment including scale up issues
  • Determination of acceptable and failure limits to establish Critical Process Parameters
  • Stability data for intermediates and final API
  • Identification of appropriate storage conditions
  • Validation documentation
  • Raw material vendor qualification

HAVE A CHEMISTRY NEED? REQUEST A QUOTE.