ChiroSil® RCA(+) and SCA (-)  are proven chiral stationary phases (CSPs) for amino acid chiral analysis. Chirosil RCA (+) and SCA (-)  have (+) or (-)-(18-Crown-6)-tetracarboxylic acid as a chiral selector, which is bonded to the silica support. The ChiroSil® CSP is manufactured for use in high-performance liquid chromatography (HPLC).

Amino Acid Chiral Analysis

  • ChiroSil® columns are ideal for the separation of chiral compounds containing almost all primary amino groups and natural and unnatural amino acids and their derivatives.
  • This CSP offers excellent performance, high efficiency, and reproducibility.
  • ChiroSil® columns are packed at 5,000 psi (~345 bar) for efficient run times.

Extreme Performance

  • The ChiroSil® stationary phase delivers long life and high reliability due to covalent bonding.
  • Change the elution order if necessary by selecting ChiroSil® RCA (+) or ChiroSil® SCA (-) column.
  • ChiroSil® works with conventional and extended solvent ranges.

Readily Available

  • ChiroSil® pre-packed columns are available in analytical and preparative dimensions.
  • This CSP is available in 5 and 10 µm particle size in commonly used column sizes. Custom column dimensions are available per agreed specification.
  • Bulk quantity purchases can be provided.


View our Chiral Applications online.
Request a free copy of our Chiral Handbook for examples of enantiomer separations.

Email the Chromatography Department ( for more information on how ChiroSil columns can help with your project.

ChiroSil® is a trademark of RStech Corporation of Daejeon, South Korea.