Probing the Use of a UHPLC Whelk-O® 1 CSP in eUHPSFC-MS for Chiral/Achiral Analysis of Naturally Occurring Cannabinoids Poster
The interest in the medical use of Cannabis Sativa L. is steadily increasing because of its therapeutic efficacy towards a wide variety of ailments and its unique chemistry, characterized by the presence of cannabinoids, which are terpenophenolic compounds that are concentrated in leaves and in the female inflorescence. The fiber type of Cannabis Sativa L., cultivated in Europe for textile production or for food (seeds, flour, and oil), has a low concentration (typically less than 0.2%) of psychoactive (-)-Δ9-tetrahydrocannabinol, [(-)-Δ9-THC]. The most abundant cannabinoid in the fiber type is cannabidiol (CBD) but there are also cannabidivarin (CBDV), cannabigerol (CBG), cannabinol (CBN) and the racemic cannabichromene (rac-CBC) , each having various therapeutic actions. The stereoselective analysis of the original composition of plant material is necessary for phenotype determination and quality control of medicinal cannabis used in therapeutic treatments.